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SYNLOGIC, INC. (SYBX)

Synlogic, Inc. does not have significant operations. It was previously engaged in the discovery and development of synthetic biotics to treat metabolic diseases. Synlogic, Inc. is based in Winchester, Massachusetts.

Sector: Pharmaceutical Preparations

Industry: Biotechnology

Synlogic, Inc. logo

Synlogic, Inc.

OTC:SYBXHealthcare
+0.00%$1.05
Mkt Cap$12.86M
Float4.97M
O/S12.25M
Inst Own0.2%
SI0.1%
Dilution
Historical Data
DateOpenHighLowCloseVolume
Key Metrics
Market Cap$12.86M
Enterprise Value--
P/E Ratio-7.93
Est. Net Cash/Share--
Institutional Ownership0.19%

based on 12.25M shares outstanding

SectorHealthcare
IndustryBiotechnology
ExchangeOTC
CountryUSUS
IPO DateSep 30, 2015
Shares Outstanding12.25M
Float4.97M
Company Overview

Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotic medicines to treat metabolic and immunological diseases in the United States.

Its therapeutic programs include SYNB1618 and SYNB1934 that are orally administered, non-systemically absorbed drug candidates, which are in Phase II clinical trials to treat phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate to treat homocystinuria; and SYNB8802, an orally administered, non-systemically absorbed drug candidate that is in Phase I clinical trial for the treatment of enteric hyperoxaluria.

The company is also developing SYNB1891, an intratumorally administered synthetic biotic medicine that is in Phase I clinical trial to treat solid tumors and lymphoma.

It has a collaboration agreement with F. Hoffmann-La Roche Ltd; Hoffmann-La Roche Inc.; and Ginkgo Bioworks, Inc. Synlogic, Inc. is headquartered in Cambridge, Massachusetts.

Leadership

Aoife Brennan

President and Chief Executive Officer

Edward Mathers

Lisa Kelly-Croswell

Michael Burgess

Employees

1

Country

US

Sector

Healthcare

Website

synlogictx.com

Analyst Coverage
Analyst Coverage
ConsensusBuy
Price Target
No price targets available
Ratings Distribution
BUY
10
HOLD
3
SELL
1
TOTAL14
Insider Trades
InsiderTypeShares
New Enterprise Associates 14, L.P. profile photoNew Enterprise Associates 14, L.P.Expiration (Long)2.64M
New Enterprise Associates 14, L.P. profile photoNew Enterprise Associates 14, L.P.Purchase2.64M
Dooley Mary Beth profile photoDooley Mary BethSale157
Shea Richard P profile photoShea Richard PGrant/Award15.0K
Flynn James P profile photoFlynn James PGrant/Award15.0K
Dooley Mary Beth profile photoDooley Mary BethSale144
Shareholders
0.2%
Institutional
(1)
0.4%
Insiderⓘ
(3)
50.9%
5%+ Owners
(2)
48.6%
Unattributed (incl. retail)ⓘ
Institutional0.2%
Insider0.4%
5%+ Beneficial50.9%
Unattributed (incl. retail)48.6%
Top Shareholders
NameShares%
Cable Car Capital, LP logo
Cable Car Capital, LP
· joint filing· may incl. warrants· filed Jul 2026
3.3M27.0%
NEA 14 GP, LTD logo
NEA 14 GP, LTD
· joint filing· may incl. warrants· filed Jul 2026
2.9M23.9%
DRW Securities, LLC logo
DRW Securities, LLC
23.8K0.2%
Shea Richard P profile photo
Shea Richard P
Director
15.5K0.1%
Flynn James P profile photo
Flynn James P
Director
15.0K0.1%
Dooley Mary Beth profile photo
Dooley Mary Beth
Head of Finance
12.7K0.1%
Sources: 13F, Form 4, 13D/13GO/S: 12.2M · as of 4 Aug 2026 · SEC cover page
Insiders & Institutional Holders

Top institutional holders

52-Week Range
$0.5401$1.87
$1.05(38th percentile)
Volume
Average Daily Volume32.25K
1.18K today vs 32.25K avg(-96%)

30d Avg

32.25K

60d Avg

24.78K

90d Avg

40.02K

Earnings
Dividend History
No dividend history available
Compliance Status
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