Spyre Therapeutics, Inc. (SYRE)
Spyre Therapeutics, Inc. (SYRE) Insider Trading
Directors, officers and holders of more than 10% of SYRE report their trades in its stock on SEC Form 4, within two business days. Each row below is one Form 4 transaction line. The one-letter code says what kind of transaction it was: only P (purchase) and S (sale) are open-market or private trades; awards, option exercises, tax withholding and gifts carry other codes.
Recent Form 4 transactions
The 50 most recent of 162 transactions on file: 0 with code P, 36 with code S and 14 with other codes.
| Date | Insider | Title | Code | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Oct 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 2,600 | $93.46 | $242,996 |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | M Exercise | 28,933 | Not measured | Not measured |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | M Exercise | 28,933 | $14.50 | $419,529 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 229 | $93.57 | $21,428 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 600 | $89.07 | $53,442 |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 7,228 | $91.35 | $660,278 |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 600 | $89.14 | $53,484 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 2,100 | $91.92 | $193,032 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 1,500 | $90.27 | $135,405 |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 4,990 | $93.37 | $465,916 |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 2,683 | $90.10 | $241,738 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | M Exercise | 7,500 | $14.50 | $108,750 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 3,071 | $92.95 | $285,449 |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 3,989 | $92.31 | $368,225 |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 2,100 | $92.70 | $194,670 |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 16,605 | $90.35 | $1,500,262 |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 100 | $93.91 | $9,391 |
| Oct 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 2,638 | $91.49 | $241,351 |
| Oct 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 400 | $89.24 | $35,696 |
| Oct 1, 2026 | Burrows Scott L | Chief Financial Officer | M Exercise | 7,500 | Not measured | Not measured |
| Sep 30, 2026 | Burrows Scott L | Chief Financial Officer | M Exercise | 17,500 | Not measured | Not measured |
| Sep 30, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 17,500 | $89.89 | $1,573,075 |
| Sep 30, 2026 | Burrows Scott L | Chief Financial Officer | M Exercise | 17,500 | $14.50 | $253,750 |
| Sep 2, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 18,232 | $89.35 | $1,629,029 |
| Sep 2, 2026 | King-Jones Heidy | See Remarks | M Exercise | 400 | $14.50 | $5,800 |
| Sep 2, 2026 | King-Jones Heidy | See Remarks | S Sale | 400 | $90.00 | $36,000 |
| Sep 2, 2026 | King-Jones Heidy | See Remarks | M Exercise | 400 | Not measured | Not measured |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 400 | $89.38 | $35,752 |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | M Exercise | 27,999 | $14.50 | $405,986 |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 2,500 | $86.36 | $215,900 |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 4,845 | $86.40 | $418,608 |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 3,700 | $88.06 | $325,822 |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 8,400 | $87.15 | $732,060 |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 16,548 | $87.20 | $1,442,986 |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | S Sale | 6,206 | $88.17 | $547,183 |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 2,016 | $88.03 | $177,468 |
| Sep 1, 2026 | King-Jones Heidy | See Remarks | M Exercise | 27,999 | Not measured | Not measured |
| Sep 1, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 400 | $89.07 | $35,628 |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | M Exercise | 7,500 | Not measured | Not measured |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | M Exercise | 7,500 | $14.50 | $108,750 |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 200 | $89.04 | $17,808 |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 900 | $86.25 | $77,625 |
| Sep 1, 2026 | Burrows Scott L | Chief Financial Officer | S Sale | 4,384 | $87.11 | $381,890 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | S Sale | 10,000 | $104.68 | $1,046,800 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | S Sale | 8,000 | $104.38 | $835,040 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | S Sale | 5,000 | $104.47 | $522,350 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | M Exercise | 5,000 | $10.39 | $51,950 |
| Aug 7, 2026 | Albers Jeffrey W. | Director | M Exercise | 5,000 | Not measured | Not measured |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 16 | $97.46 | $1,559 |
| Aug 3, 2026 | Turtle Cameron | Chief Executive Officer | S Sale | 1,392 | $96.82 | $134,773 |
The full Form 4 history is on the SYRE company page (Insider Trades card, View all).
Questions about this data
Which insider transactions are open-market trades?
Code P (open market or private purchase) and code S (open market or private sale). Code F is shares withheld to pay tax on vesting stock, A is an award from the company, M and X are option exercises and G is a gift. None of those is the insider choosing to buy or sell in the market.
How quickly are insider trades reported?
A Form 4 is due before the end of the second business day after the trade. The date shown is the transaction date from the form.
Who has to file Form 4?
Officers, directors and beneficial owners of more than 10% of a class of the company’s registered equity, under Section 16 of the Securities Exchange Act.
Look up any code in the Form 4 transaction code reference, or read Form 4 codes explained.