Joseph Klein III

CIK: 0001206369

Transaction Breakdown

Open Market Buys (P)0 (0.0%)

High conviction signal

Open Market Sales (S)13 (46.4%)

Position reduction

Option Exercises (M)11 (39.3%)

Derivative conversions

Awards (A)4 (14.3%)

Compensation grants

Other (G, F, J, C, D, …)0 (0.0%)

Gifts, tax withholding, conversions, dispositions to the issuer and other codes

Companies & Roles (1)

IONS

IONIS PHARMACEUTICALS INC

Director

Discretionary Trading P&L

Holdings

Transaction History (28 total)

IONS
IONIS PHARMACEUTICALS INC
Jul 1, 2026
Exercise(M)
Direct
11.5K shares at avg. $39.94$460K
IONS
IONIS PHARMACEUTICALS INC
Jul 1, 2026
Award(A)
Restricted Stock Unit
Direct
2.3K shares-
IONS
IONIS PHARMACEUTICALS INC
Jul 1, 2026
Award(A)
Non-Qualified Stock Option (right to buy)
Direct
5.4K shares-
IONS
IONIS PHARMACEUTICALS INC
Jul 1, 2026
Sale(S)
Direct
11.4K shares at avg. $79.04$903K
IONS
IONIS PHARMACEUTICALS INC
Jul 1, 2026
Sale(S)
Direct
99 shares at avg. $79.45$8K
IONS
IONIS PHARMACEUTICALS INC
May 1, 2026
Exercise(M)
Direct
10.1K shares at avg. $47.11$476K
IONS
IONIS PHARMACEUTICALS INC
May 1, 2026
Sale(S)
Direct
1.4K shares at avg. $74.45$107K
IONS
IONIS PHARMACEUTICALS INC
May 1, 2026
Sale(S)
Direct
8.7K shares at avg. $73.35$637K
IONS
IONIS PHARMACEUTICALS INC
Apr 1, 2026
Exercise(M)
Direct
12K shares at avg. $38.06$457K
IONS
IONIS PHARMACEUTICALS INC
Apr 1, 2026
Exercise(M)
Direct
10.3K shares at avg. $41.08$424K
IONS
IONIS PHARMACEUTICALS INC
Apr 1, 2026
Sale(S)
Direct
20.1K shares at avg. $75.50$1.5M
IONS
IONIS PHARMACEUTICALS INC
Apr 1, 2026
Sale(S)
Direct
2.2K shares at avg. $75.95$168K
IONS
IONIS PHARMACEUTICALS INC
Mar 3, 2026
Sale(S)
Direct
6.8K shares at avg. $80.00$543K
IONS
IONIS PHARMACEUTICALS INC
Mar 3, 2026
Sale(S)
Direct
1K shares at avg. $80.82$82K
IONS
IONIS PHARMACEUTICALS INC
Mar 3, 2026
Exercise(M)
Direct
12K shares at avg. $40.05$481K
IONS
IONIS PHARMACEUTICALS INC
Mar 3, 2026
Exercise(M)
Direct
4K shares at avg. $42.88$172K
IONS
IONIS PHARMACEUTICALS INC
Mar 3, 2026
Sale(S)
Direct
13.5K shares at avg. $79.17$1.1M
IONS
IONIS PHARMACEUTICALS INC
Nov 25, 2025
Exercise(M)
Indirect
4K shares-
IONS
IONIS PHARMACEUTICALS INC
Nov 25, 2025
Sale(S)
Indirect
4K shares at avg. $80.00$320K
IONS
IONIS PHARMACEUTICALS INC
Nov 25, 2025
Exercise(M)
Indirect
4K shares-
IONS
IONIS PHARMACEUTICALS INC
Nov 25, 2025
Sale(S)
Indirect
4K shares at avg. $80.00$320K
IONS
IONIS PHARMACEUTICALS INC
Nov 25, 2025
Exercise(M)
Indirect
4K shares-
IONS
IONIS PHARMACEUTICALS INC
Nov 25, 2025
Sale(S)
Indirect
4K shares at avg. $80.00$320K
IONS
IONIS PHARMACEUTICALS INC
Sep 3, 2025
Sale(S)
Indirect
28K shares at avg. $60.00$1.7M
IONS
IONIS PHARMACEUTICALS INC
Sep 3, 2025
Exercise(M)
Indirect
12K shares-

		Type	Shares	Price		Ownership
Jul 1, 2026	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	11,518	$39.94	$460,029	Direct
Jul 1, 2026	IONS IONIS PHARMACEUTICALS INC	Award(A) Restricted Stock Unit	2,301	-	-	Direct
Jul 1, 2026	IONS IONIS PHARMACEUTICALS INC	Award(A) Non-Qualified Stock Option (right to buy)	5,369	-	-	Direct
Jul 1, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	11,419	$79.04	$902,551	Direct
Jul 1, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	99	$79.45	$7,866	Direct
May 1, 2026	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	10,111	$47.11	$476,329	Direct
May 1, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	1,431	$74.45	$106,534	Direct
May 1, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	8,680	$73.35	$636,704	Direct
Apr 1, 2026	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	12,000	$38.06	$456,720	Direct
Apr 1, 2026	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	10,321	$41.08	$423,987	Direct
Apr 1, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	20,105	$75.50	$1,517,988	Direct
Apr 1, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	2,216	$75.95	$168,314	Direct
Mar 3, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	6,794	$80.00	$543,486	Direct
Mar 3, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	1,012	$80.82	$81,788	Direct
Mar 3, 2026	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	12,000	$40.05	$480,600	Direct
Mar 3, 2026	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	4,000	$42.88	$171,520	Direct
Mar 3, 2026	IONS IONIS PHARMACEUTICALS INC	Sale(S)	13,526	$79.17	$1,070,908	Direct
Nov 25, 2025	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	4,000	-	-	Indirect
Nov 25, 2025	IONS IONIS PHARMACEUTICALS INC	Sale(S)	4,000	$80.00	$320,000	Indirect
Nov 25, 2025	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	4,000	-	-	Indirect
Nov 25, 2025	IONS IONIS PHARMACEUTICALS INC	Sale(S)	4,000	$80.00	$320,000	Indirect
Nov 25, 2025	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	4,000	-	-	Indirect
Nov 25, 2025	IONS IONIS PHARMACEUTICALS INC	Sale(S)	4,000	$80.00	$320,000	Indirect
Sep 3, 2025	IONS IONIS PHARMACEUTICALS INC	Sale(S)	28,000	$60.00	$1,680,000	Indirect
Sep 3, 2025	IONS IONIS PHARMACEUTICALS INC	Exercise(M)	12,000	-	-	Indirect

1-25 of 28 transactions

About KLEIN JOSEPH III

KLEIN JOSEPH III (SEC CIK 0001206369) files insider reports with the SEC as Director of IONIS PHARMACEUTICALS INC (IONS).

Signal8 holds 8 ownership filings by KLEIN JOSEPH III, all Form 4s, filed between Jul 2, 2025 and Jul 6, 2026. Those filings report 28 transactions, from Jul 1, 2025 to Jul 1, 2026. Signal8's Form 4 history starts in Sep 2024.

The business address on KLEIN JOSEPH III's filings is in CARLSBAD, CA.

Recent filings by KLEIN JOSEPH III

Jul 1, 2026: Option exercise of IONS shares (Form 4, code M).
Jul 1, 2026: Grants or awards of IONS derivative securities (2 lines, Form 4, code A).
Jul 1, 2026: Open-market sales of IONS shares (2 lines, Form 4, code S).
May 1, 2026: Option exercise of IONS shares (Form 4, code M).
May 1, 2026: Open-market sales of IONS shares (2 lines, Form 4, code S).

Other insiders filing for IONIS PHARMACEUTICALS INC (IONS)

Devers Shannon L., EVP, Chief Human Resources Ofc
Swayze Eric, EVP Research
BENNETT C FRANK, EVP, Chief Scientific Officer
O'NEIL PATRICK R., EVP CLO & General Counsel
Monia Brett P, Chief Executive Officer
Birchler Brian, EVP, Corp and Development Ops

How to read Form 4 transaction codes