Fred A. Middleton

CIK: 0001267959

Transaction Breakdown

Open Market Buys (P)5 (33.3%)

High conviction signal

Open Market Sales (S)0 (0.0%)

Position reduction

Option Exercises (M)0 (0.0%)

Derivative conversions

Awards (A)4 (26.7%)

Compensation grants

Other (G, F, J, C, D, …)6 (40.0%)

Gifts, tax withholding, conversions, dispositions to the issuer and other codes

Companies & Roles (2)

CALC

CalciMedica, Inc.

Director10% Owner

CMRX

CHIMERIX INC

Director

Discretionary Trading P&L

Holdings

Transaction History (15 total)

CALC
CalciMedica, Inc.
Jun 25, 2026
Purchase(P)
Indirect
249K shares at avg. $0.80$200K
CALC
CalciMedica, Inc.
Jun 24, 2025
Award(A)
Director Stock Option (Right to Buy)
Direct
10K shares-
CALC
CalciMedica, Inc.
Jun 24, 2025
Award(A)
Director Stock Option (Right to Buy)
Direct
19.7K shares-
CALC
CalciMedica, Inc.
Jun 24, 2025
Award(A)
Director Stock Option (Right to Buy)
Direct
6.6K shares-
CALC
CalciMedica, Inc.
Jun 24, 2025
Award(A)
Director Stock Option (Right to Buy)
Direct
10K shares-
CMRX
CHIMERIX INC
Apr 21, 2025
Disposition(D)
Indirect
40K shares at avg. $8.55$342K
CMRX
CHIMERIX INC
Apr 21, 2025
Disposition(D)
Indirect
60K shares at avg. $8.55$513K
CMRX
CHIMERIX INC
Apr 21, 2025
Disposition(D)
Indirect
2.8M shares at avg. $8.55$23.7M
CMRX
CHIMERIX INC
Apr 21, 2025
Disposition(D)
Indirect
531.9K shares at avg. $8.55$4.5M
CMRX
CHIMERIX INC
Apr 21, 2025
Disposition(D)
Direct
207.5K shares at avg. $8.55$1.8M
CALC
CalciMedica, Inc.
Dec 6, 2024
Purchase(P)
Direct
4.8K shares at avg. $2.65$13K
CALC
CalciMedica, Inc.
Nov 1, 2024
Purchase(P)
Indirect
877 shares at avg. $3.75$3K
CALC
CalciMedica, Inc.
Nov 1, 2024
Purchase(P)
Indirect
86.9K shares at avg. $3.75$326K
CALC
CalciMedica, Inc.
Nov 1, 2024
Purchase(P)
Direct
20K shares at avg. $3.75$75K
CMRX
CHIMERIX INC
Oct 28, 2024
Gift(G)
Indirect
60K shares-

		Type	Shares	Price		Ownership
Jun 25, 2026	CALC CalciMedica, Inc.	Purchase(P)	248,972	$0.80	$199,999	Indirect
Jun 24, 2025	CALC CalciMedica, Inc.	Award(A) Director Stock Option (Right to Buy)	10,000	-	-	Direct
Jun 24, 2025	CALC CalciMedica, Inc.	Award(A) Director Stock Option (Right to Buy)	19,687	-	-	Direct
Jun 24, 2025	CALC CalciMedica, Inc.	Award(A) Director Stock Option (Right to Buy)	6,562	-	-	Direct
Jun 24, 2025	CALC CalciMedica, Inc.	Award(A) Director Stock Option (Right to Buy)	10,000	-	-	Direct
Apr 21, 2025	CMRX CHIMERIX INC	Disposition(D)	40,000	$8.55	$342,000	Indirect
Apr 21, 2025	CMRX CHIMERIX INC	Disposition(D)	60,000	$8.55	$513,000	Indirect
Apr 21, 2025	CMRX CHIMERIX INC	Disposition(D)	2,776,093	$8.55	$23,735,595	Indirect
Apr 21, 2025	CMRX CHIMERIX INC	Disposition(D)	531,861	$8.55	$4,547,412	Indirect
Apr 21, 2025	CMRX CHIMERIX INC	Disposition(D)	207,523	$8.55	$1,774,322	Direct
Dec 6, 2024	CALC CalciMedica, Inc.	Purchase(P)	4,800	$2.65	$12,720	Direct
Nov 1, 2024	CALC CalciMedica, Inc.	Purchase(P)	877	$3.75	$3,289	Indirect
Nov 1, 2024	CALC CalciMedica, Inc.	Purchase(P)	86,867	$3.75	$325,751	Indirect
Nov 1, 2024	CALC CalciMedica, Inc.	Purchase(P)	20,000	$3.75	$75,000	Direct
Oct 28, 2024	CMRX CHIMERIX INC	Gift(G)	60,000	-	$0	Indirect

1-15 of 15 transactions

About Middleton Fred A

Middleton Fred A (SEC CIK 0001267959) files insider reports with the SEC as Director of CalciMedica, Inc. (CALC) and Director of CHIMERIX INC (CMRX).

Signal8 holds 6 ownership filings by Middleton Fred A, all Form 4s, filed between Oct 30, 2024 and Jun 29, 2026. Those filings report 15 transactions, from Oct 28, 2024 to Jun 25, 2026. Signal8's Form 4 history starts in Sep 2024.

The business address on Middleton Fred A's filings is in LA JOLLA, CA.

Recent filings by Middleton Fred A

Jun 25, 2026: Open-market purchase of CALC shares (Form 4, code P).
Jun 24, 2025: Grants or awards of CALC derivative securities (4 lines, Form 4, code A).
Apr 21, 2025: Disposition to issuer transactions of CMRX shares (5 lines, Form 4, code D).
Dec 6, 2024: Open-market purchase of CALC shares (Form 4, code P).
Nov 1, 2024: Open-market purchases of CALC shares (3 lines, Form 4, code P).

Other insiders filing for CalciMedica, Inc. (CALC)

Glicklich Alan, Director
Zaytsev Evgeny, Director
Guerard Frederic, Director
Shaw Allan, Director
WILSON ROBERT N, Director
Hebbar Sudarshan, Chief Medical Officer

How to read Form 4 transaction codes