Michael Mano

CIK: 0001837741

Transaction Breakdown

Open Market Buys (P)0 (0.0%)

High conviction signal

Open Market Sales (S)5 (45.5%)

Position reduction

Option Exercises (M)0 (0.0%)

Derivative conversions

Awards (A)6 (54.5%)

Compensation grants

Other (G, F, J, C, D, …)0 (0.0%)

Gifts, tax withholding, conversions, dispositions to the issuer and other codes

Companies & Roles (1)

KPTI

Karyopharm Therapeutics Inc.

Officer

Discretionary Trading P&L

Holdings

Transaction History (11 total)

KPTI
Karyopharm Therapeutics Inc.
May 14, 2026
Sale(S)
Direct
266 shares at avg. $9.50$3K
KPTI
Karyopharm Therapeutics Inc.
May 13, 2026
Award(A)
Direct
700 shares-
KPTI
Karyopharm Therapeutics Inc.
Mar 2, 2026
Sale(S)
Direct
3.5K shares at avg. $9.41$33K
KPTI
Karyopharm Therapeutics Inc.
Jan 31, 2026
Award(A)
Direct
32.4K shares-
KPTI
Karyopharm Therapeutics Inc.
Oct 15, 2025
Award(A)
Direct
43.7K shares-
KPTI
Karyopharm Therapeutics Inc.
Sep 15, 2025
Sale(S)
Direct
234 shares at avg. $6.43$2K
KPTI
Karyopharm Therapeutics Inc.
Sep 12, 2025
Award(A)
Direct
612 shares-
KPTI
Karyopharm Therapeutics Inc.
Mar 4, 2025
Sale(S)
Direct
2.8K shares at avg. $6.29$18K
KPTI
Karyopharm Therapeutics Inc.
Feb 28, 2025
Award(A)
Direct
2.3K shares-
KPTI
Karyopharm Therapeutics Inc.
Feb 28, 2025
Award(A)
Direct
3.3K shares-
KPTI
Karyopharm Therapeutics Inc.
Sep 4, 2024
Sale(S)
Direct
4K shares at avg. $0.72$3K

		Type	Shares	Price		Ownership
May 14, 2026	KPTI Karyopharm Therapeutics Inc.	Sale(S)	266	$9.50	$2,527	Direct
May 13, 2026	KPTI Karyopharm Therapeutics Inc.	Award(A)	700	-	$0	Direct
Mar 2, 2026	KPTI Karyopharm Therapeutics Inc.	Sale(S)	3,526	$9.41	$33,178	Direct
Jan 31, 2026	KPTI Karyopharm Therapeutics Inc.	Award(A)	32,415	-	$0	Direct
Oct 15, 2025	KPTI Karyopharm Therapeutics Inc.	Award(A)	43,650	-	-	Direct
Sep 15, 2025	KPTI Karyopharm Therapeutics Inc.	Sale(S)	234	$6.43	$1,505	Direct
Sep 12, 2025	KPTI Karyopharm Therapeutics Inc.	Award(A)	612	-	-	Direct
Mar 4, 2025	KPTI Karyopharm Therapeutics Inc.	Sale(S)	2,793	$6.29	$17,568	Direct
Feb 28, 2025	KPTI Karyopharm Therapeutics Inc.	Award(A)	2,250	-	-	Direct
Feb 28, 2025	KPTI Karyopharm Therapeutics Inc.	Award(A)	3,333	-	-	Direct
Sep 4, 2024	KPTI Karyopharm Therapeutics Inc.	Sale(S)	3,971	$0.72	$2,866	Direct

1-11 of 11 transactions

About Mano Michael

Mano Michael (SEC CIK 0001837741) files insider reports with the SEC as EVP, CLO&Secretary of Karyopharm Therapeutics Inc. (KPTI).

Signal8 holds 8 ownership filings by Mano Michael, all Form 4s, filed between Sep 5, 2024 and May 15, 2026. Those filings report 11 transactions, from Sep 4, 2024 to May 14, 2026. Signal8's Form 4 history starts in Sep 2024.

The business address on Mano Michael's filings is in NEWTON, MA.

Recent filings by Mano Michael

May 14, 2026: Open-market sale of KPTI shares (Form 4, code S).
May 13, 2026: Grant or award of KPTI shares (Form 4, code A).
Mar 2, 2026: Open-market sale of KPTI shares (Form 4, code S).
Jan 31, 2026: Grant or award of KPTI shares (Form 4, code A).
Oct 15, 2025: Grant or award of KPTI shares (Form 4, code A).

Other insiders filing for Karyopharm Therapeutics Inc. (KPTI)

Abate Kristin, Chief Accounting Officer
Poulton Stuart, EVP, Chief Development Officer
Oliger Christy J., Director
PAKIANATHAN DEEPIKA, Director
Schor Chen, Director
Su Zhen, Director

How to read Form 4 transaction codes