Fleming Harold Edward
SEC insider (Form 3/4/5 filer). CIK 0001857250. Director at Sionna Therapeutics, Inc. (SION) and 2 other issuers. 7 reported Form 4/5 transactions since Sep 2024; latest on Jun 17, 2026. Located in BOSTON, MA.
Companies Fleming Harold Edward has filed insider reports for
- Sionna Therapeutics, Inc. (SION): Director
- Upstream Bio, Inc. (UPB): Director
- CRISPR Therapeutics AG (CRSP): Director
Fleming Harold Edward
CIK: 0001857250
Transaction Breakdown
High conviction signal
Position reduction
Derivative conversions
Compensation grants
Gifts, tax withholding, conversions, dispositions to the issuer and other codes
Discretionary Trading P&L
Holdings
Transaction History (7 total)
- Jun 17, 2026SION
Sionna Therapeutics, Inc.
AwardDirectNon-Qualified Stock Option (right to buy)
17.3K shares- - Jun 9, 2026UPB
Upstream Bio, Inc.
AwardDirectStock Option (Right to Buy)
17.1K shares- - Jun 5, 2026CRSP
CRISPR Therapeutics AG
AwardDirectStock Option (Right to Buy)
13K shares- - Jun 12, 2025SION
Sionna Therapeutics, Inc.
AwardDirectNon-Qualified Stock Option (right to buy)
20K shares- - Jun 10, 2025UPB
Upstream Bio, Inc.
AwardDirectStock Option (Right to Buy)
17.1K shares- - Jun 5, 2025CRSP
CRISPR Therapeutics AG
AwardDirectStock Option (Right to Buy)
13K shares- - Oct 10, 2024UPB
Upstream Bio, Inc.
AwardDirectStock Option (Right to Buy)
17.1K shares-
| Type | Shares | Price | Ownership | |||
|---|---|---|---|---|---|---|
| Jun 17, 2026 |  SION Sionna Therapeutics, Inc. | Award Non-Qualified Stock Option (right to buy) | 17,340 | - | - | Direct |
| Jun 9, 2026 |  UPB Upstream Bio, Inc. | Award Stock Option (Right to Buy) | 17,096 | - | - | Direct |
| Jun 5, 2026 |  CRSP CRISPR Therapeutics AG | Award Stock Option (Right to Buy) | 13,000 | - | - | Direct |
| Jun 12, 2025 | SION Sionna Therapeutics, Inc. | Award Non-Qualified Stock Option (right to buy) | 19,959 | - | - | Direct |
| Jun 10, 2025 | UPB Upstream Bio, Inc. | Award Stock Option (Right to Buy) | 17,096 | - | - | Direct |
| Jun 5, 2025 | CRSP CRISPR Therapeutics AG | Award Stock Option (Right to Buy) | 13,000 | - | - | Direct |
| Oct 10, 2024 | UPB Upstream Bio, Inc. | Award Stock Option (Right to Buy) | 17,096 | - | - | Direct |
1-7 of 7 transactions