Karen Firestone

CIK: 0001969821

Transaction Breakdown

Open Market Buys (P)3 (42.9%)

High conviction signal

Open Market Sales (S)0 (0.0%)

Position reduction

Option Exercises (M)2 (28.6%)

Derivative conversions

Awards (A)2 (28.6%)

Compensation grants

Other (G, F, J, C, D, …)0 (0.0%)

Gifts, tax withholding, conversions, dispositions to the issuer and other codes

Companies & Roles (1)

AMLX

Amylyx Pharmaceuticals, Inc.

Director

Discretionary Trading P&L

Holdings

Transaction History (7 total)

AMLX
Amylyx Pharmaceuticals, Inc.
Aug 31, 2026
Exercise(M)
Direct
25K shares at avg. $1.76$44K
AMLX
Amylyx Pharmaceuticals, Inc.
Aug 31, 2026
Exercise(M)
Direct
25K shares at avg. $5.05$126K
AMLX
Amylyx Pharmaceuticals, Inc.
Jun 4, 2026
Award(A)
Stock Option (right to buy)
Direct
24.4K shares-
AMLX
Amylyx Pharmaceuticals, Inc.
May 21, 2026
Purchase(P)
Direct
3.8K shares at avg. $13.51$51K
AMLX
Amylyx Pharmaceuticals, Inc.
Dec 23, 2025
Purchase(P)
Direct
8.1K shares at avg. $12.45$101K
AMLX
Amylyx Pharmaceuticals, Inc.
Jun 5, 2025
Award(A)
Stock Option (right to buy)
Direct
25K shares-
AMLX
Amylyx Pharmaceuticals, Inc.
Sep 5, 2024
Purchase(P)
Direct
50K shares at avg. $2.13$107K

		Type	Shares	Price		Ownership
Aug 31, 2026	AMLX Amylyx Pharmaceuticals, Inc.	Exercise(M)	25,000	$1.76	$44,000	Direct
Aug 31, 2026	AMLX Amylyx Pharmaceuticals, Inc.	Exercise(M)	25,000	$5.05	$126,250	Direct
Jun 4, 2026	AMLX Amylyx Pharmaceuticals, Inc.	Award(A) Stock Option (right to buy)	24,372	-	-	Direct
May 21, 2026	AMLX Amylyx Pharmaceuticals, Inc.	Purchase(P)	3,800	$13.51	$51,338	Direct
Dec 23, 2025	AMLX Amylyx Pharmaceuticals, Inc.	Purchase(P)	8,100	$12.45	$100,845	Direct
Jun 5, 2025	AMLX Amylyx Pharmaceuticals, Inc.	Award(A) Stock Option (right to buy)	25,000	-	-	Direct
Sep 5, 2024	AMLX Amylyx Pharmaceuticals, Inc.	Purchase(P)	50,000	$2.13	$106,590	Direct

1-7 of 7 transactions

About Firestone Karen

Firestone Karen (SEC CIK 0001969821) files insider reports with the SEC as Director of Amylyx Pharmaceuticals, Inc. (AMLX).

Signal8 holds 6 ownership filings by Firestone Karen, all Form 4s, filed between Sep 9, 2024 and Sep 2, 2026. Those filings report 7 transactions, from Sep 5, 2024 to Aug 31, 2026. Signal8's Form 4 history starts in Sep 2024.

The business address on Firestone Karen's filings is in CAMBRIDGE, MA.

Recent filings by Firestone Karen

Aug 31, 2026: Option exercises of AMLX shares (2 lines, Form 4, code M).
Jun 4, 2026: Grant or award of AMLX derivative securities (Form 4, code A).
May 21, 2026: Open-market purchase of AMLX shares (Form 4, code P).
Dec 23, 2025: Open-market purchase of AMLX shares (Form 4, code P).
Jun 5, 2025: Grant or award of AMLX derivative securities (Form 4, code A).

Other insiders filing for Amylyx Pharmaceuticals, Inc. (AMLX)

MILNE GEORGE M JR, Director
Bedrosian Camille L, Chief Medical Officer
FRATES JAMES M, Chief Financial Officer
Mazzariello Gina, Chief Legal Officer
Klee Justin B., Co-Chief Executive Officer
Cohen Joshua B, Co-Chief Executive Officer

How to read Form 4 transaction codes