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Opaleye Management Inc.

SEC insider (Form 3/4/5 filer). CIK 0001595855. 10% Owner at Alpha Cognition Inc. (ACOG) and 7 other issuers. 240 reported Form 4/5 transactions since Sep 2024; latest on Oct 26, 2026. Located in BOSTON, MA.

Companies Opaleye Management Inc. has filed insider reports for

  • Alpha Cognition Inc. (ACOG): 10% Owner
  • Grace Therapeutics, Inc. (GRCE): 10% Owner
  • Sol-Gel Technologies Ltd. (SLGL): 10% Owner
  • Eton Pharmaceuticals, Inc. (ETON): 10% Owner
  • SANUWAVE Health, Inc. (SNWV): 10% Owner
  • HARROW, INC. (HROW): 10% Owner
  • CODEXIS, INC. (CDXS): 10% Owner
  • Protara Therapeutics, Inc. (TARA): 10% Owner
Opaleye Management Inc. profile photo

Opaleye Management Inc.

CIK: 0001595855

Transaction Breakdown

Open Market Buys (P)182 (75.8%)

High conviction signal

Open Market Sales (S)58 (24.2%)

Position reduction

Option Exercises (M)0 (0.0%)

Derivative conversions

Awards (A)0 (0.0%)

Compensation grants

Other (G, F, J, C, D, …)0 (0.0%)

Gifts, tax withholding, conversions, dispositions to the issuer and other codes

Companies & Roles (8)

Alpha Cognition Inc. logo
ACOG

Alpha Cognition Inc.

10% Owner
Grace Therapeutics, Inc. logo
GRCE

Grace Therapeutics, Inc.

10% Owner
Sol-Gel Technologies Ltd. logo
SLGL

Sol-Gel Technologies Ltd.

10% Owner
Eton Pharmaceuticals, Inc. logo
ETON

Eton Pharmaceuticals, Inc.

10% Owner
SANUWAVE Health, Inc. logo
SNWV

SANUWAVE Health, Inc.

10% Owner
HARROW, INC. logo
HROW

HARROW, INC.

10% Owner
CODEXIS, INC. logo
CDXS

CODEXIS, INC.

10% Owner
Protara Therapeutics, Inc. logo
TARA

Protara Therapeutics, Inc.

10% Owner

Discretionary Trading P&L

Holdings

Transaction History (240 total)

  • Grace Therapeutics, Inc. logo
    GRCE

    Grace Therapeutics, Inc.

    Oct 26, 2026
    Purchase
    Indirect
    66.4K shares at avg. $1.77$117K
  • Alpha Cognition Inc. logo
    ACOG

    Alpha Cognition Inc.

    Oct 23, 2026
    Purchase
    Indirect
    15K shares at avg. $8.23$123K
  • Grace Therapeutics, Inc. logo
    GRCE

    Grace Therapeutics, Inc.

    Oct 22, 2026
    Purchase
    Indirect
    21.4K shares at avg. $1.93$41K
  • Alpha Cognition Inc. logo
    ACOG

    Alpha Cognition Inc.

    Oct 22, 2026
    Purchase
    Indirect
    17.1K shares at avg. $8.33$143K
  • Grace Therapeutics, Inc. logo
    GRCE

    Grace Therapeutics, Inc.

    Oct 19, 2026
    Purchase
    Indirect
    4.3K shares at avg. $1.88$8K
  • Alpha Cognition Inc. logo
    ACOG

    Alpha Cognition Inc.

    Oct 16, 2026
    Purchase
    Indirect
    14.3K shares at avg. $8.23$118K
  • Grace Therapeutics, Inc. logo
    GRCE

    Grace Therapeutics, Inc.

    Oct 16, 2026
    Purchase
    Indirect
    36.3K shares at avg. $1.89$69K
  • Alpha Cognition Inc. logo
    ACOG

    Alpha Cognition Inc.

    Oct 15, 2026
    Purchase
    Indirect
    22.7K shares at avg. $8.43$191K
  • Grace Therapeutics, Inc. logo
    GRCE

    Grace Therapeutics, Inc.

    Oct 15, 2026
    Purchase
    Indirect
    23.5K shares at avg. $1.95$46K
  • Grace Therapeutics, Inc. logo
    GRCE

    Grace Therapeutics, Inc.

    Oct 14, 2026
    Purchase
    Indirect
    11.2K shares at avg. $1.93$22K

1-10 of 240

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