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Kazia Therapeutics Announces Sovargen Co. Doses First Patient in Phase 1b/2a Trial of Paxalisib for Rare Seizure Disorders

$KZIAPress releaseSep 22, 2026, 7:30 AM ETRead the release

Sovargen has dosed the first patient in a Phase 1b/2a trial of paxalisib for intractable epilepsy linked to focal cortical dysplasia type 2 and tuberous sclerosis complex, triggering a $2 million development milestone payment to Kazia. Under the March 2024 exclusive licensing deal, Sovargen develops and commercializes paxalisib for mTORopathy-related epilepsies worldwide excluding mainland China, Hong Kong, Macao and Taiwan; Kazia remains eligible for up to $17 million in further milestones plus sub-licensing revenue share and royalties on net sales.

Key figures

Drug Name
paxalisib
Phase Of Trial
Phase 1b/2a
Milestone payment usd
2000000
Additional milestones potential usd
17000000

AI analysis

Red flags3 · Pro

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    KZIA: Kazia Therapeutics Announces Sovargen Co. Doses First Patient in Phase 1b/2a Trial of Paxalisib for Rare Seizure Disorders — AI Analysis | Signal8