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AC Immune Reports Positive Safety & Immunogenicity at week-100 in Part 1 of VacSYn Phase 2 Trial of ACI-7104

$ACIUPress releaseSep 23, 2026, 7:00 AM ETRead the release

AC Immune reported positive week-100 results from Part 1 of the VacSYn Phase 2 trial of ACI-7104 in early-stage Parkinson's disease, with all primary endpoints of safety, tolerability and immunogenicity met. 100% of treated patients developed antibodies against the a-syn target after three immunizations, with robust antibody penetration into the CSF and preliminary signals of target engagement.

Key figures

Drug Name
ACI-7104
Phase Of Trial
Phase 2
Trial name
VacSYn
Data timepoint
week-100
Patients treated
25
Placebo patients
9
Fda meeting timing
early 2027
Patients randomized
34
Immunogenicity response rate
100%

AI analysis

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