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Relay Therapeutics Announces Clinical Data for Zovegalisib plus Atirmociclib Triplet Combination Supportive of Further Development in Frontline Metastatic Breast Cancer

$RLAYPress releaseApr 27, 2026, 6:00 AM ETRead the release

Relay Therapeutics reported positive Phase 1/2 data for its zovegalisib triplet combination, showing a 44% objective response rate in heavily pre-treated, median third-line metastatic breast cancer patients. Based on the tolerability and efficacy profile, the company plans to advance the regimen into a randomized Phase 3 trial for frontline patients, expected to initiate in early 2027.

Key figures

Drug Name
zovegalisib
Phase Of Trial
Phase 1/2
Median follow up months
7.4
Patients at or below rp3d
62
Patients evaluated for response
34

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