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NeuroPace Highlights Expanding Clinical Evidence Leadership with Published 3-Year Post-Approval Study (PAS) Results in Neurology and NAUTILUS Presentation at AAN 2026

$NPCEPress releaseApr 27, 2026, 7:30 AM ETRead the release

NeuroPace announced the publication of 3-year results from its Post-Approval Study in Neurology, showing an 82% median seizure reduction in drug-resistant focal epilepsy among 324 patients. The company also presented 12- and 18-month data from its NAUTILUS trial at AAN 2026, demonstrating a 77% median reduction in generalized tonic-clonic seizures and significant safety improvements for idiopathic generalized epilepsy.

Key figures

Drug Name
RNS System
Phase Of Trial
Post-Approval Study / NAUTILUS trial
Pas study centers
32
Pas study patients
324
Pas seizure reduction median
82%
Nautilius injury events decline
30%
Nautilius rescue medication reduction
44%
Nautilius gtc seizure reduction median
77%
Nautilius clinical global impression change
80%

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