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Preliminary Results of Open-Label Study in Adult Short Bowel Syndrome Patients with Intestinal Failure (SBS-IF) with Jaguar Health's Crofelemer Accepted for Presentation at Annual American College of Gastroenterology Meeting

$JAGXPress releaseSep 29, 2026, 4:30 AM ETRead the release

Jaguar Health's family company Napo Pharmaceuticals announced acceptance of an abstract with preliminary open-label crofelemer data in adult short bowel syndrome with intestinal failure (SBS-IF) for presentation at ACG 2026, held October 9-14 in Nashville. A separate multicenter, randomized double-blind placebo-controlled Phase 2 trial in adult Type 1 SBS patients without colon-in-continuity is ongoing, with results expected early in the second half of 2027. Prior data in pediatric intestinal failure patients showed substantial reductions in weekly parenteral support needs with no significant clinical or laboratory abnormalities.

Key figures

Drug Name
crofelemer (powder for oral solution)
Phase Of Trial
Phase 2
Mvid nda filing
mid-2027
Phase2 sbs data timing
early second half of 2027

AI analysis

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    JAGX: Preliminary Results of Open-Label Study in Adult Short Bowel Syndrome Patients with Intestinal Failure (SBS-IF) with Jaguar Health's Crofelemer Accepted for Presentation at Annual American College of Gastroenterology Meeting — AI Analysis | Signal8