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Jupiter Neurosciences Announces First Patient Dosed in Phase 2a RESET Trial in Parkinson’s Disease and Exploration of Strategic Options to Maximize Shareholder Value

$JUNSPress releaseOct 6, 2026, 11:15 AM ETRead the release

Jupiter Neurosciences dosed the first patient in its Phase 2a RESET trial (NCT07592767) evaluating JOTROL, its micellar trans-resveratrol formulation, in Parkinson's disease. The multicenter, randomized, placebo-controlled study will enroll roughly 30 patients treated orally for 12 weeks, assessing safety, pharmacokinetics and biomarkers. Simultaneously, Jupiter has retained Tungsten Advisors to explore strategic options — including asset sales, licensing, partnerships or a business combination — to maximize shareholder value, with no assurance of any transaction. Georgetown University is the study sponsor; the Parkinson's franchise addresses an estimated 1.1 million U.S.

Key figures

Drug Name
JOTROL (micellar trans-resveratrol)
Phase Of Trial
Phase 2a
Trial name
RESET
Randomization
1:1:1 to two JOTROL dose levels or placebo
Trial identifier
NCT07592767
Planned enrollment
approximately 30 patients
Treatment duration
12 weeks

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