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GH Research Announces Publication of Phase 2a Postpartum Depression Results

$GHRSPress releaseJun 4, 2026, 7:00 AM ETRead the release

GH Research published full results from its Phase 2a open-label trial of inhaled mebufotenin (GH001) in postpartum depression, showing a mean MADRS reduction of -35.4 points. All 10 enrolled patients achieved remission within two hours of dosing, with effects sustained through Day 8 and no serious adverse events reported.

Key figures

Drug Name
GH001 (mebufotenin)
Phase Of Trial
Phase 2a
Sample size ppd
10
Remission rate ppd
100%
Madrs reduction ppd
-35.4
Madrs reduction trd
-15.5

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