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Structure Therapeutics Announces Publication in Nature Medicine Highlighting Phase 2b ACCESS Program of Aleniglipron for Obesity

$GPCRPress releaseJun 5, 2026, 4:05 PM ETRead the release

Structure Therapeutics published Phase 2b ACCESS trial data for aleniglipron in Nature Medicine, highlighting dose-dependent weight loss up to 16.2% in the open-label extension. The data demonstrates a favorable tolerability profile with a low 10.4% discontinuation rate and suggests patients can successfully restart or up-titrate dosing after interruptions without significant recurrence of vomiting.

Key figures

Drug Name
aleniglipron
Phase Of Trial
Phase 2b
Phase 3 start
Q3 2026
Starting dose mg
2.5
Max weight loss pct
16.2%
Discontinuation rate pct
10.4%

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