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Robust Phase 2b Efficacy and Favorable Tolerability Support Monthly Dosing for Pfizer’s GLP-1 RA Berobenatide

$PFEPress releaseJun 6, 2026, 9:00 AM ETRead the release

Pfizer presented robust Phase 2b data for berobenatide, an investigational monthly GLP-1 receptor agonist, at the ADA Scientific Sessions. The VESPER-1 study showed a non-placebo-adjusted weight loss of 15.9% with no plateau at 32 weeks, while VESPER-2 demonstrated a 2.2% reduction in HbA1c in patients with type 2 diabetes.

Key figures

Drug Name
berobenatide (PF’3944)
Phase Of Trial
Phase 2b
Hba1c reduction
2.2%
Weight loss percent
15.9%
Total obesity trials
20+
Planned phase3 trials
10

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