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Stoke Therapeutics Presents Data Supporting the Disease-Modifying Potential of STK-002 in Autosomal Dominant Optic Atrophy (ADOA) at the American Academy of Ophthalmology (AAO) 2026 Annual Meeting

$STOKPress releaseOct 12, 2026, 8:00 AM ETRead the release

Stoke Therapeutics presented natural history and preclinical data at AAO 2026 supporting the disease-modifying potential of STK-002, an antisense oligonucleotide targeting OPA1 deficiency in Autosomal Dominant Optic Atrophy. Dosing is complete in the first two cohorts of the Phase 1 OSPREY study, with the third cohort expected to complete by year-end 2026 and initial safety and efficacy data anticipated in H1 2027.

Key figures

Drug Name
STK-002
Phase Of Trial
Phase 1
Data timing
initial safety and efficacy data anticipated in H1 2027
Falcon enrollment
47
Osprey sites active
8

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