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Natera and TransCode Therapeutics to Collaborate on Phase 2a Trial of TTX-MC138 in Colorectal Cancer

$NTRAPress releaseOct 13, 2026, 7:30 AM ETRead the release

Natera announced a strategic collaboration with TransCode Therapeutics to use the Signatera MRD test to identify MRD-positive colorectal cancer patients for TransCode's Phase 2a trial of TTX-MC138. The trial, run by Quantum Leap Healthcare Collaborative within the PRE-I-SPY program, marks that platform's first expansion beyond breast cancer into colorectal cancer.

Key figures

Drug Name
TTX-MC138
Phase Of Trial
Phase 2a
Trial Id
NCT05868226
Signatera Publications
400+ peer-reviewed publications supporting Natera tests

AI analysis

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    NTRA: Natera and TransCode Therapeutics to Collaborate on Phase 2a Trial of TTX-MC138 in Colorectal Cancer — AI Analysis | Signal8