Skip to main content
Signal8

/C O R R E C T I O N - AbbVie/

$ABBVPress releaseOct 18, 2026, 9:18 PM ETRead the release

AbbVie announced its largest-ever ESMO program, with new and updated data across seven solid tumor assets presented at the 2026 ESMO Congress in Madrid (Oct 23-27). Temab-A (telisotuzumab adizutecan) posted strong Phase 1 results: 30% ORR and 14.7-month median OS in colorectal cancer (vs 10.2 months standard of care) and 50-63% ORR in NSCLC, supporting ongoing global Phase 3 trials; the asset recently received two FDA Breakthrough Therapy Designations. ABBV-706 showed a 56% ORR in 2L+ small cell lung cancer (82% in 2L-only), and ABBV-1480 delivered a 61.9% ORR with 15.2-month median PFS in first-line PD-L1-positive NSCLC, both advancing in Phase 3.

Key figures

Drug Name
Temab-A (telisotuzumab adizutecan); ABBV-706; ABBV-969; ABBV-1480 (RC148); alveltamig; Emrelis; Elahere
Phase Of Trial
Phase 1 data with multiple ongoing Phase 3 studies
Temab A crc orr
30%
Temab A crc median os
14.7 months vs 10.2 months standard of care
Abbv1480 1 L nsclc orr
61.9%
Abbv706 sclc 2 Lonly orr
82%
Abbv706 sclc 2 Lplus orr
56%
Temab A nsclc egfr wt orr
50%
Temab A nsclc egfr mut orr
63%
Abbv1480 1 L nsclc median pfs
15.2 months

AI analysis

Red flags2 · Pro

The rest of the AI analysis, red flags and sentiment are part of Signal8 Pro.

AI-generated analysis of a public disclosure. Not investment advice; verify against the original document.