Current Screening Thresholds May Miss Half of Patients with Primary Aldosterone, a Leading Cause of Severe High Blood Pressure, Finds Study in Hypertension
A Quest Diagnostics-led study published in Hypertension found current 2025 Endocrine Society screening criteria would identify only 13.0% of patients with primary aldosteronism, while broader permissive criteria identified 26.2% -- roughly double. The study analyzed deidentified lab results from over 60,449 U.S. patients tested by Quest, with collaborators from Mass General Brigham, Harvard Medical School and UT Southwestern.
Key figures
- Cohort size
- 60449
- Afib odds ratio pra lt 025
- 2.62
- Us adults with hypertension
- nearly 120 million
- Detection rate 2025 criteria
- 13.0%
- Pa prevalence in hypertension
- 5-10%
- Detection rate permissive criteria
- 26.2%
- Hypertension odds ratio pra lt 050
- 1.27
- Potential pa diagnosis rate if confirmed
- 25-30%
AI analysis
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