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Myriad Genetics Releases New MONSTAR-SCREEN-3 Data Demonstrating the Potential of Ultra-Sensitive MRD Detection in Colorectal and Pancreatic Cancers

$MYGNPress releaseOct 22, 2026, 9:05 AM ETRead the release

Myriad Genetics announced new MONSTAR-SCREEN-3 data showing its WGS-based Precise MRD platform detected residual disease with ultra-sensitivity in resectable colorectal and pancreatic cancers. In colorectal cancer, post-surgical ctDNA was detected ahead of all observed recurrences with a median four-month lead time; more than half of positives were found below 100 parts per million. In pancreatic cancer, a historically low-shedding tumor type, personalized panels were built for all evaluable patients and MRD detection at one month correlated with worse recurrence-free survival.

Key figures

Drug Name
Precise MRD
Phase Of Trial
MONSTAR-SCREEN-3 (ongoing study)
Max panel variants
1000
Median lead time months
4
Ctdna detection threshold ppm
100

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