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Ardelyx Presents Real-World Data at ASN Kidney Week 2026 Showing Serum Phosphate Reductions Following XPHOZAH® (tenapanor) Initiation With or Without Phosphate Binders

$ARDXPress releaseOct 23, 2026, 4:01 PM ETRead the release

Ardelyx presented real-world data at ASN Kidney Week 2026 showing serum phosphate reductions following XPHOZAH initiation in more than 1,400 adults on dialysis, both with and without phosphate binders. Adjusted mean phosphate reductions at six months ranged from 0.80 to 1.55 mg/dL, with 60-70% of patients remaining on tenapanor at 180 days.

Key figures

Drug Name
XPHOZAH (tenapanor)
Phase Of Trial
real-world analysis (>1,400 dialysis patients, 6-month follow-up)
Patients analyzed
1400
Persistence at 180 days
60% to 70%
Probability below 5.5 mg d L
16% to 41%
Adjusted mean phosphate reduction month6
0.80 to 1.55 mg/dL

AI analysis

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    ARDX: Ardelyx Presents Real-World Data at ASN Kidney Week 2026 Showing Serum Phosphate Reductions Following XPHOZAH® (tenapanor) Initiation With or Without Phosphate Binders — AI Analysis | Signal8