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Oncotelic Announces PDAOAI Identification of a Four-Gene Liver Cancer Signature

$OTLCPress releaseOct 26, 2026, 8:00 AM ETRead the release

Oncotelic announced publication of a peer-reviewed Biomedicines study using its AI-driven PDAOAI platform to identify a four-gene prognostic signature (FKBP1A, EIF4E, RRAGC, PPARGC1A) in hepatocellular carcinoma. The signature was independently validated in a Japanese HCC cohort of 203 patients and defines patient stratification for planned clinical trials of Sapu003, an intravenous formulation of everolimus.

Key figures

Drug Name
Sapu003 (intravenous everolimus)
Target vectors
approximately 100 billion
Gmp bio interest
45%
Gene signature count
4
Validation cohort patients
203
Platform index pubmed abstracts
approximately 29 million

AI analysis

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