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Equillium Announces First Subject Dosed in Phase 1 Clinical Trial of EQ504

$EQPress releaseOct 26, 2026, 8:30 AM ETRead the release

Equillium dosed the first subject in a Phase 1 trial of EQ504, an oral colon-targeted AhR modulator for inflammatory diseases, with topline proof-of-mechanism data expected in Q2 2027. The milestone triggered the closing of an additional $20 million tranche under its August 2025 private placement — 14,957,260 shares at $0.57 and 20,130,457 pre-funded warrants at $0.5669 — bringing total placement proceeds to roughly $50 million. With the new capital, cash runway extends into 2029, and a placebo-controlled Phase 2 proof-of-concept study in ulcerative colitis is planned for the second half of 2027.

Key figures

Drug Name
EQ504
Deal Value Usd
20000000
Phase Of Trial
Phase 1
Offering Price
0.57
Cash runway
into 2029
Subjects enrolled
70
Prefunded warrants
20130457
Topline data timing
Q2 2027
Prefunded warrant price
0.5669
Placement tranche shares
14957260
Total placement proceeds
$50 million

AI analysis

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    EQ: Equillium Announces First Subject Dosed in Phase 1 Clinical Trial of EQ504 — AI Analysis | Signal8