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Charles River Leverages Virtual Control Groups in GLP Studies

$CRLPress releaseOct 27, 2026, 8:00 AM ETRead the release

Charles River announced its Virtual Control Group (VCG) methodology will be used in an upcoming GLP-compliant toxicology study for Ipsen, digitally replacing a portion of concurrent control animals in safety testing. VCGs combine historical control data, advanced statistics, and AI-powered analytics under the company's Alternative Methods Advancement Project, targeting up to a 12% reduction in animal use without compromising regulatory-grade rigor.

Key figures

Animal use reduction
Up to 12% where scientifically appropriate

AI analysis

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