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Acrivon Announces Late-Breaking Oral Plenary Presentation of Early Phase 1/2 Clinical Results in AP3-Predicted Tumors for its First-in-Class WEE1/PKMYT1 Inhibitor ACR-2316 at the 38th EORTC-NCI-AACR Symposium

$ACRVPress releaseOct 29, 2026, 8:00 AM ETRead the release

Acrivon announced that dose escalation data for ACR-2316, its first-in-class oral WEE1/PKMYT1 inhibitor, will be presented in a late-breaking oral plenary session at the 38th EORTC-NCI-AACR Symposium on November 20, 2026. The Phase 1/2 data show durable clinical activity in heavily pretreated, AP3-predicted tumors, including a confirmed complete response in a squamous NSCLC patient after four prior lines of therapy and responses in endometrial and lung cancers, with several patients on treatment over one year.

Key figures

Drug Name
ACR-2316
Phase Of Trial
Phase 1/2
Symposium
38th EORTC-NCI-AACR Symposium
Abstract number
11LBA
Presentation date
November 20, 2026
Median prior lines therapy
3

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