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New Data Presented at AHA Scientific Sessions 2026 Demonstrate That CARDAMYST® (etripamil) Nasal Spray Converted Recurrent PSVT to Normal Heart Rhythm in Patients with Prior Catheter Ablation

$MISTPress releaseNov 2, 2026, 8:00 AM ETRead the release

New Phase 3 RAPID subgroup data show CARDAMYST (etripamil) nasal spray converted 66.7% of post-ablation PSVT patients to normal sinus rhythm within 30 minutes, versus 20% on placebo. The prior-ablation subgroup was small (N=11) and the analysis was descriptive and not powered for between-group comparison, though responses mirrored the broader RAPID efficacy population.

Key figures

Drug Name
CARDAMYST (etripamil) nasal spray
Phase Of Trial
Phase 3
Subgroup size
11
Trial total randomized
692
Conversion rate placebo
20.0%
Conversion rate etripamil
66.7%
Prior ablation pct of randomized
6.6%

AI analysis

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    MIST: New Data Presented at AHA Scientific Sessions 2026 Demonstrate That CARDAMYST® (etripamil) Nasal Spray Converted Recurrent PSVT to Normal Heart Rhythm in Patients with Prior Catheter Ablation — AI Analysis | Signal8