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Seaport Therapeutics Reports First Quarter 2026 Financial Results and Highlights Recent Corporate and Clinical Progress

$SPTXPress releaseJun 8, 2026, 7:05 AM ETRead the release

Seaport Therapeutics reported Q1 2026 results with a net loss of $25.4 million, driven by increased R&D spend of $21.4 million as its lead programs advance. The company highlighted positive clinical progress: GlyphAgo showed a 6.8-fold increase in bioavailability compared to unmodified agomelatine, potentially avoiding liver toxicity issues, while enrollment in the pivotal Phase 2b BUOY-1 trial for GlyphAllo is on track with topline data expected in H1 2027. Seaport closed an upsized IPO raising $260 million in gross proceeds, bringing total cash and investments to over $470 million and extending its operational runway into 2029. Dr.

Key figures

Revenue
0
Net loss
25408000
Ga expenses
6112000
Rd expenses
21431000
Runway year
2029
Ipo proceeds
260000000
Cash and investments
212642000
Glyphallo target enrollment
360
Glyphago bioavailability increase
6.8-fold

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