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Spruce Biosciences Announces Long-Term Tralesinidase Alfa Enzyme Replacement Therapy Data in Sanfilippo Syndrome Type B (MPS IIIB) Presented at the 18th International MPS Symposium

$SPRBPress releaseJun 8, 2026, 4:05 PM ETRead the release

Spruce Biosciences presented long-term clinical data for its lead asset, tralesinidase alfa (TA-ERT), at the 18th International MPS Symposium. The data, covering 22 patients over six years, showed that TA-ERT stabilized cognitive, communication, and motor skills relative to the decline seen in untreated natural history patients.

Key figures

Drug Name
tralesinidase alfa
Patient count
22
Study duration years
6
Total doses administered
6000

AI analysis

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    SPRB: Spruce Biosciences Announces Long-Term Tralesinidase Alfa Enzyme Replacement Therapy Data in Sanfilippo Syndrome Type B (MPS IIIB) Presented at the 18th International MPS Symposium — AI Analysis | Signal8