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Kymera Therapeutics Announces First Participant Dosed in Phase 1 Trial of Oral IRAK4 Degrader, KT-485, and Milestone Achievement Under Sanofi Collaboration

$KYMRPress releaseJun 9, 2026, 7:00 AM ETRead the release

Kymera Therapeutics announced the first participant has been dosed in the Phase 1 trial of KT-485, an oral IRAK4 degrader for immunological diseases. The dosing event triggered a $20 million milestone payment from partner Sanofi, which is leading development and commercialization for the program outside of oncology.

Key figures

Drug Name
KT-485 (SAR447971)
Phase Of Trial
Phase 1
Milestone payment
20000000
Potential milestones
975000000

AI analysis

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    KYMR: Kymera Therapeutics Announces First Participant Dosed in Phase 1 Trial of Oral IRAK4 Degrader, KT-485, and Milestone Achievement Under Sanofi Collaboration — AI Analysis | Signal8