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Immunome Announces First Patient Dosed in Phase 1 Trial Evaluating IM-1617, a Potential First-in-Class ADC, in Patients with Advanced Solid Tumors

$IMNMPress releaseJun 11, 2026, 7:30 AM ETRead the release

Immunome announced the first patient dosing in the Phase 1, first-in-human trial of IM-1617, a potential first-in-class antibody-drug conjugate (ADC) for advanced solid tumors. IM-1617 incorporates Immunome’s proprietary HC74 topoisomerase I inhibitor payload and targets an undisclosed receptor tyrosine kinase. The open-label, multicenter study will evaluate safety, tolerability, and preliminary anti-tumor activity in patients with colorectal, lung, and breast cancers.

Key figures

Drug Name
IM-1617
Phase Of Trial
Phase 1
Payload
HC74
Mechanism
TOP1 inhibitor
Asset type
ADC

AI analysis

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    IMNM: Immunome Announces First Patient Dosed in Phase 1 Trial Evaluating IM-1617, a Potential First-in-Class ADC, in Patients with Advanced Solid Tumors — AI Analysis | Signal8