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CytoDyn Announces First Patient Dosed in Phase 2a Study in Collaboration with Weill Cornell Medicine Evaluating Leronlimab in Alzheimer’s Disease

$CYDYPress releaseJun 11, 2026, 8:30 AM ETRead the release

CytoDyn announced the first patient has been dosed in the SALIENT-AD Phase 2a study, a collaboration with Weill Cornell Medicine evaluating leronlimab in Alzheimer’s disease. The open-label proof-of-concept study will enroll 10 to 20 patients over age 50 with early-stage, biomarker-confirmed Alzheimer’s, receiving weekly subcutaneous injections for 12 weeks. The primary endpoint assesses changes in brain inflammation and microglial activation using PET imaging, while secondary endpoints include safety, cognitive assessments, and blood-based biomarkers.

Key figures

Drug Name
leronlimab
Phase Of Trial
Phase 2a
Patient count
10 to 20
Treatment duration
12 weeks

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