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Celldex Presents Positive First-in-Human Results from Phase 1 Study of Novel Bispecific CDX-622 at the European Academy of Allergy and Clinical Immunology Annual Meeting

$CLDXPress releaseJun 14, 2026, 5:15 AM ETRead the release

Celldex presented positive Phase 1 results for CDX-622, a novel bispecific antibody targeting soluble SCF and TSLP, at the EAACI Annual Meeting. The data showed rapid, dose-dependent, and durable reductions in serum tryptase, confirming mast cell depletion, with no dose-limiting toxicities or serious adverse events.

Key figures

Drug Name
CDX-622
Phase Of Trial
Phase 1
Mechanism
bispecific antibody targeting soluble SCF and TSLP
Study participants
80

AI analysis

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    CLDX: Celldex Presents Positive First-in-Human Results from Phase 1 Study of Novel Bispecific CDX-622 at the European Academy of Allergy and Clinical Immunology Annual Meeting — AI Analysis | Signal8