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Cadrenal Therapeutics Advances Multi-Indication Strategy for CAD-1005; Launches Phase 2a Acute Kidney Injury (CSA-AKI) Clinical Plan to Accelerate Pharma Partnering at Upcoming BIO 2026

$CVKDPress releaseJun 15, 2026, 8:30 AM ETRead the release

Cadrenal Therapeutics plans to initiate a Phase 2a proof-of-concept trial of its lead asset CAD-1005 to prevent Acute Kidney Injury (AKI) in high-risk cardiac surgery patients. The trial targets Cardiac Surgery-Associated AKI (CSA-AKI), a condition affecting 35,000 U.S. patients annually with no approved targeted therapies, representing a $1 billion market.

Key figures

Drug Name
CAD-1005
Phase Of Trial
Phase 2a
Csa aki market size usd
$1 billion
Hospital mortality increase
8-fold
Csa aki us patients annually
35000

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