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Entera Reports Robust Preclinical Data for EB612 (Oral LA-PTH(1-34)) for Hypoparathyroidism and EB618 (Oral GLP-1/Glucagon) for Obesity at ENDO 2026

$ENTXPress releaseJun 16, 2026, 8:33 AM ETRead the release

Entera Bio reported robust preclinical data at ENDO 2026 for EB612, an oral peptide for hypoparathyroidism, and EB618, an oral GLP-1/glucagon agonist for obesity. EB612 demonstrated sustained calcium increases and bioavailability across multiple animal models, supporting a planned IND submission in late 2026, while EB618 showed dose-proportional pharmacokinetics in primates.

Key figures

Drug Name
EB612, EB618
Phase Of Trial
Preclinical
Eb613 phase 2 n
161
Eb612 ind timeline
late 2026
Eb618 safety margin
>10x clinical dose

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