Skip to main content
Signal8

4DMT Completes Enrollment for 4FRONT-2 Global Phase 3 Clinical Trial of 4D-150 in Wet AMD

$FDMTPress releaseJun 29, 2026, 8:00 AM ETRead the release

4D Molecular Therapeutics completed enrollment for the 4FRONT-2 global Phase 3 trial of 4D-150 in wet AMD approximately four months ahead of schedule and with over-enrollment anticipated at more than 500 patients. The 4FRONT-2 trial is a randomized, double-masked study comparing 4D-150 to aflibercept, with 52-week topline data expected in the second half of 2027. The company also noted that 4FRONT-1 topline data is anticipated in the first half of 2027.

Key figures

Drug Name
4D-150
Phase Of Trial
Phase 3
4front1 data readout
H1 2027
4front2 data readout
H2 2027
Anticipated enrollment
>500

AI analysis

The rest of the AI analysis, red flags and sentiment are part of Signal8 Pro.

AI-generated analysis of a public disclosure. Not investment advice; verify against the original document.

    FDMT: 4DMT Completes Enrollment for 4FRONT-2 Global Phase 3 Clinical Trial of 4D-150 in Wet AMD — AI Analysis | Signal8