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BillionToOne's Northstar Response® Is a Stronger Predictor of Immunotherapy Outcomes Than Standard-of-Care Imaging for Cancer Patients in Peer-Reviewed Study

$BLLNPress releaseJun 29, 2026, 12:40 PM ETRead the release

BillionToOne announced the publication of a peer-reviewed study in The Journal of Liquid Biopsy demonstrating that its Northstar Response assay is a stronger predictor of survival than standard-of-care imaging for immunotherapy patients. Data from 142 patients across 12 solid tumor types showed molecular progression was the dominant independent predictor of survival with a hazard ratio of 5.3, detecting progression a median of 62 days before imaging.

Key figures

Tumor types
12
Patients enrolled
142
Lead time median days
62
Molecular rebound rate
1 in 4
Hazard ratio molecular progression
5.3
Hazard ratio combined progression landmark
13.8
Hazard ratio combined progression longitudinal
19.7

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