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InflaRx Announces Advancement of Izicopan in ANCA-Associated Vasculitis and Select Renal Diseases

$IFRXPress releaseMay 6, 2026, 8:25 AM ETRead the release

InflaRx announced a strategic advancement of its oral C5aR inhibitor izicopan into ANCA-associated vasculitis (AAV), with Phase 2 planning underway and an eye toward an expedited regulatory path. The company also intends to establish rapid proof of concept in other renal diseases including aHUS, IgAN, and C3G, with open-label studies expected to generate data next year.

Key figures

Drug Name
izicopan
Phase Of Trial
Phase 2
Cash runway
through 2029
C5a blockade
≥90%
Market potential hs
$1.5 billion per year

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