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Spyre Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

$SYREPress releaseMay 5, 2026, 8:00 AM ETRead the release

Spyre Therapeutics reported positive topline induction data from Part A of the Phase 2 SKYLINE trial for SPY001, achieving the primary endpoint with a 9.2-point reduction in RHI score. The company strengthened its balance sheet with $463 million in gross proceeds from a recent offering, bringing pro forma cash to $1.2 billion with a runway into the second half of 2029.

Key figures

Net loss
69005000
Cash runway
into second half of 2029
Ga expenses
15230000
Rd expenses
60411000
Cash position
741500000
Shares outstanding
78839858

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