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Spero Therapeutics and Innovent Biologics Announce Exclusive License for SP001 (IBI355), a Phase 2-Ready Third-Generation Anti-CD40L Antibody

$SPROPress releaseJul 14, 2026, 6:00 AM ETRead the release

Spero Therapeutics has secured exclusive global rights, excluding Greater China, to Innovent Biologics' SP001 (IBI355), a third-generation anti-CD40L antibody currently targeting immune-mediated diseases. Under the agreement, Innovent is eligible to receive approximately US$1.1 billion in total milestone payments along with tiered royalties, while Spero plans to initiate a Phase 2 trial for IgG4-related disease in Q2 2027.

Key figures

Drug Name
SP001 (IBI355)
Deal Value Usd
US$1.1 billion
Phase Of Trial
Phase 2

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