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Tempest Unveils Next-Generation In Vivo CAR-T Pipeline, with First Clinical Study Planned for the Fourth Quarter of 2026

$TPSTPress releaseJul 15, 2026, 7:00 AM ETRead the release

Tempest Therapeutics announced plans to advance TPST-4003, its lead in vivo CAR-T candidate, into an investigator-initiated clinical study for myasthenia gravis and multiple sclerosis in the fourth quarter of 2026. The trial is expected to enroll approximately 10 patients, with initial safety and pharmacodynamic data anticipated in the first half of 2027.

Key figures

Trial enrollment
approximately 10 patients
First dosing date
fourth quarter of 2026
Initial data date
first half of 2027

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