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Akebia Therapeutics Announces Initiation of a Phase 2 Basket Trial to Study Ebribafusp, a Next-Generation Complement Inhibitor in Rare Kidney Diseases

$AKBAPress releaseAug 3, 2026, 8:00 AM ETRead the release

Akebia Therapeutics initiated a Phase 2 basket trial to evaluate Ebribafusp, a complement inhibitor acquired from Q32 Bio, for rare complement-mediated kidney diseases including IgAN, lupus nephritis, and C3 glomerulopathy. The open-label study expects to enroll up to 30 patients receiving weekly subcutaneous dosing for 26 weeks, with initial data anticipated in 2027.

Key figures

Drug Name
Ebribafusp
Phase Of Trial
Phase 2
Prevalence us
200000
Dosing frequency
weekly subcutaneous
Data readout year
2027
Patient enrollment
30
Trial duration weeks
26

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