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Theriva™ Biologics Announces First Patient Dosed in VIRAGE2 Phase 2a Clinical Trial to Evaluate More Frequent Dosing of VCN-01 (zabilugene almadenorepvec) in First-Line Patients with Metastatic Pancreatic Ductal Adenocarcinoma

$TOVXPress releaseAug 6, 2026, 8:00 AM ETRead the release

Theriva Biologics dosed the first patient in the VIRAGE2 Phase 2a trial, evaluating more frequent dosing of VCN-01 in first-line metastatic pancreatic ductal adenocarcinoma (PDAC). The single-arm study involves six evaluable patients and aims to refine the dosing regimen for a future pivotal Phase 3 trial, with enrollment expected in H2 2026 and initial data anticipated by Q3 2027.

Key figures

Drug Name
VCN-01 (zabilugene almadenorepvec)
Phase Of Trial
Phase 2a
Trial ids
["EUCT: 2026-525566-21-00","NCT07701486"]
Evaluable patients
6
Initial data readout
Q3 2027
Enrollment completion
H2 2026

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