Largest Prospective Study in General-Risk Pregnancies Strengthens Evidence for cfDNA Fetal Risk Assessment as a Primary Screen for Recessive Conditions
BillionToOne announced the publication of the largest prospective study evaluating cfDNA fetal risk assessment in general-risk pregnancies in *The Green Journal*. The study of 2,212 pregnant carriers demonstrated that the Unity Fetal Risk Screen achieved 94.4% sensitivity and 99.5% specificity, identifying more affected pregnancies than traditional carrier screening.
Key figures
- Sensitivity
- 94.4%
- Specificity
- 99.5%
- Outcome rate
- 98.6%
- Study participants
- 2212
- Negative predictive value
- >99.9%
AI analysis
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