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Olema Oncology Announces Clinical Trial Collaboration and Supply Agreement with Bayer to Evaluate OP-3136 in Combination with NUBEQA® (darolutamide) in Metastatic Castration-Resistant Prostate Cancer

$OLMAPress releaseMay 26, 2026, 7:00 AM ETRead the release

Olema Oncology announced a clinical trial collaboration and supply agreement with Bayer to evaluate its KAT6 inhibitor OP-3136 in combination with Bayer’s NUBEQA (darolutamide). The Phase 1b/2 study will assess safety and preliminary anti-tumor activity in approximately 36 patients with metastatic castration-resistant prostate cancer (mCRPC), with initiation expected in the second half of 2026. This marks the first clinical collaboration for OP-3136, expanding its development beyond breast cancer.

Key figures

Drug Name
OP-3136
Phase Of Trial
Phase 1b/2
Study start
H2 2026
Patient count
36

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