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Natera and Angiex Partner to Assess Response to Investigational Nuclear-Delivered Antibody-Drug Conjugate™ Using Signatera™

$NTRAPress releaseAug 27, 2026, 6:00 AM ETRead the release

Natera partnered with Angiex to deploy its Signatera test in a Phase I trial of AGX101, a novel Nuclear-Delivered Antibody-Drug Conjugate for advanced solid tumors. The collaboration will use longitudinal circulating tumor DNA monitoring to assess treatment response, aiming to complement radiologic assessments for patients with unresectable or metastatic disease.

Key figures

Drug Name
AGX101
Phase Of Trial
Phase I
Target antigen
TM4SF1
Clinical trial id
NCT06440005

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