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Pacira BioSciences Reports Real-World Study Showing EXPAREL® Use Was Associated with Reduced Opioid Use and Healthcare Costs in Patients Undergoing Total Shoulder Arthroplasty

$PCRXPress releaseMay 27, 2026, 8:00 AM ETRead the release

Pacira BioSciences presented real-world study findings at ISPOR 2026 showing EXPAREL use was associated with reduced opioid consumption and lower healthcare costs in patients undergoing total shoulder arthroplasty. The retrospective analysis covered more than 6,400 opioid-naïve Medicare Advantage patients, comparing EXPAREL against standard-of-care analgesia using data from Optum Clinformatics.

Key figures

Study population size
6400
Opioid consumption reduction
78%

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