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Protagonist Therapeutics, Inc (PTGX) Form 10-Q — Aug 5, 2026

$PTGXForm 10-QFiled Aug 5, 2026, 4:17 PM ET0001104659-26-091123Original filing

Protagonist Therapeutics swung to Q2 2026 net income of $162.8 million ($2.47 basic, $2.29 diluted EPS) on license and collaboration revenue of $213.5 million, versus a $34.8 million net loss on $5.5 million revenue in the year-ago quarter. Six-month net income was $166.6 million on $269.8 million of revenue. The profit surge came from collaboration payments: a $50.0 million JNJ milestone earned upon FDA approval of ICOTYDE for plaque psoriasis, and $202.5 million recognized under the Takeda Collaboration Agreement after Protagonist exercised its right on April 28, 2026 to opt out of the 50/50 U.S. profit-share on rusfertide.

Key figures

Eps
2.47 basic / 2.29 diluted (Q2 2026); 2.54 basic / 2.35 diluted (six months)
Revenue
213475000
Net Income
162849000
Total Assets
885544000
Cash Position
420078000
Shares Outstanding
64708285
Cfo10b5 1 Plan
CFO plan adopted June 30, 2026 to sell up to 73,214 shares plus 50% of RSU (21,346 shares) and PSU (12,800 shares) net shares through September 30, 2027
Q22025 Revenue
5546000
Jnj Royalty Range
6%-10% with sales milestones up to 425.0 million
Six Month Revenue
269843000
Takeda Opt Out Fee
additional 200.0 million opt-out fee
Total Liabilities
44001000
Six Month Net Income
166632000
Jnj Milestone Q12026
50.0 million earned upon FDA approval of ICOTYDE for plaque psoriasis
Stockholders Equity
841543000
Takeda Opt Out Payment
200.0 million triggered by April 28, 2026 opt-out ($192.4 million recognized in Q2)
Jnj Cumulative Payments
387.5 million from inception through June 30, 2026
Jnj Upcoming Milestones
25.0M/45.0M (second indication), 35.0M/50.0M (third indication)
Rusfertide Royalty Range
14%-29% tiered, ~21% weighted-average at $1.5 billion annual net sales
Rusfertide Sales Milestones
up to 775.0 million
Six Month Operating Cash Flow
170109000
Rusfertide Fda Approval Milestone
75.0 million upon FDA approval of rusfertide NDA
Cash Cash Equivalents Marketable Securities
849.5 million (vs 646.0 million at Dec 31, 2025)

Price after filing

1 day: 0.0%7 days: +11.9%30 days: +9.6%

Close on the filing date to close N calendar days later (from $135.81). Historical, not a forecast.

AI analysis

Red flags4 · Pro

The rest of the AI analysis, red flags and sentiment are part of Signal8 Pro.

AI-generated analysis of a public disclosure. Not investment advice; verify against the original document.

    Protagonist Therapeutics, Inc (PTGX) Form 10-Q — Aug 5, 2026: AI Analysis | Signal8