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IONIS PHARMACEUTICALS INC (IONS) Form 8-K — Jul 29, 2026

$IONSForm 8-KItems 2.02, 9.01Filed Jul 29, 2026, 7:31 AM ET0001140361-26-029960Original filing

Ionis Pharmaceuticals reported financial results for the second quarter of 2026, with total revenue of $268 million. Excluding a one-time payment received in the prior year, revenue increased 56% year-over-year driven by product sales and royalties, though the company recorded a net loss of $115 million compared to net income of $124 million in the prior year quarter. Cash, cash equivalents and short-term investments were $2.1 billion as of June 30, 2026, down from $2.7 billion at year-end 2025 due to debt repayment. Commercial momentum continued with DAWNZERA generating $26 million in net product sales and TRYNGOLZA contributing $5 million following its recent approval.

Key figures

Revenue
268
Cash Position
2055
Dawnzera sales q2 millions
26
Wainua royalty q2 millions
16
Tryngolza sales q2 millions
5
Spinraza royalty q2 millions
54
Cardio ttransform primary endpoint
missed

Price after filing

1 day: -1.2%7 days: -1.6%30 days: +11.6%

Close on the filing date to close N calendar days later (from $55.96). Historical, not a forecast.

AI analysis

Red flags3 · Pro

The rest of the AI analysis, red flags and sentiment are part of Signal8 Pro.

AI-generated analysis of a public disclosure. Not investment advice; verify against the original document.

    IONIS PHARMACEUTICALS INC (IONS) Form 8-K — Jul 29, 2026: AI Analysis | Signal8